Sequence Detail

ID/Version

Q9JJV9 Q3UH91 E9Q1D2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Sodium channel protein type 5 subunit alpha {ECO:0000305};AltName: Full=Sodium channel protein cardiac muscle subunit alpha;AltName: Full=Sodium channel protein type V subunit alpha;AltName: Full=Voltage-gated sodium channel subunit alpha Na

Provider

SWISS-PROT

Sequence

Polypeptide 2019 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Scn5a	sodium channel, voltage-gated, type V, alpha	158	111	4	26

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108205 Zimmer T, et al., Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants. Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H1007-17
J:117345 Wagner S, et al., Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest. 2006 Dec;116(12):3127-38
J:187546 Wang C, et al., Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts. Circ Res. 2011 Sep 16;109(7):775-82
J:200449 Chakrabarti S, et al., MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):392-401
J:255706 Huang L, et al., Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population. J Am Heart Assoc. 2018 Jan 6;7(1)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87