Sequence Detail

ID/Version

Q9JJS6 Q6K1L5 Q9ERN9 Q8C6N5 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Beta,beta-carotene 15,15'-dioxygenase {ECO:0000305|PubMed:11092891}; EC=1.13.11.63 {ECO:0000269|PubMed:11092891, ECO:0000269|PubMed:15951442};AltName: Full=Beta-carotene dioxygenase 1;AltName: Full=Beta-carotene oxygenase 1 {ECO:0000

Provider

SWISS-PROT

Sequence

Polypeptide 566 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bco1	beta-carotene oxygenase 1	34	112	4	3

Sequence references in MGI

J:67765 Redmond TM, et al., Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase. J Biol Chem. 2001 Mar 2;276(9):6560-5
J:68396 Yan W, et al., Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium. Genomics. 2001 Mar 1;72(2):193-202
J:84122 Boulanger A, et al., Identification of beta-carotene 15, 15'-monooxygenase as a peroxisome proliferator-activated receptor target gene. FASEB J. 2003 Jul;17(10):1304-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100279 Poliakov E, et al., Key role of conserved histidines in recombinant mouse beta-carotene 15,15'-monooxygenase-1 activity. J Biol Chem. 2005 Aug 12;280(32):29217-23