Sequence Detail

ID/Version

Q9JJJ7 Q9CWT0 A2AC30 Q9JJJ8 A2AC32 A2AC33 Q9JJJ9 Q9JJK0 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein-serine O-palmitoleoyltransferase porcupine {ECO:0000305}; Short=mPORC; EC=2.3.1.250 {ECO:0000269|PubMed:17141155, ECO:0000269|PubMed:24798332};

Provider

SWISS-PROT

Sequence

Polypeptide 461 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Porcn	porcupine O-acyltransferase	42	108	4	26

Sequence references in MGI

J:63226 Tanaka K, et al., The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem. 2000 Jul;267(13):4300-11
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203794 Rios-Esteves J, et al., Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Rep. 2013 Sep 26;4(6):1072-81
J:216033 Rios-Esteves J, et al., Identification of key residues and regions important for porcupine-mediated Wnt acylation. J Biol Chem. 2014 Jun 13;289(24):17009-19
J:219624 Takada R, et al., Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell. 2006 Dec;11(6):791-801