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Sequence Detail
Q9JJ28 Q8VI44 Q8K095 (UniProt | EBI) Last sequence update: 2000-10-01
Last annotation update: 2019-05-08
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RecName: Full=Protein flightless-1 homolog;
Polypeptide 1271 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Flii flightless I actin binding protein 17 2 9 14
Sequence references in MGI J:63555 Campbell HD, et al., Fliih, the murine homologue of the Drosophila melanogaster flightless I gene: nucleotide sequence, chromosomal mapping and overlap with Llglh. DNA Seq. 2000;11(1-2):29-40
J:76249 Campbell HD, et al., Fliih, a gelsolin-related cytoskeletal regulator essential for early mammalian embryonic development. Mol Cell Biol. 2002 May;22(10):3518-26
J:88187 Lee YH, et al., Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity. Mol Cell Biol. 2004 Mar;24(5):2103-17
J:182076 Kopecki Z, et al., Regulation of focal adhesions by flightless i involves inhibition of paxillin phosphorylation via a Rac1-dependent pathway. J Invest Dermatol. 2011 Jul;131(7):1450-9
J:187457 Mohammad I, et al., Flightless I is a focal adhesion-associated actin-capping protein that regulates cell migration. FASEB J. 2012 Aug;26(8):3260-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory