Sequence Detail

ID/Version

Q9JIS5 Q80TT0 Q8R0R5 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Synaptic vesicle glycoprotein 2A; Short=Synaptic vesicle protein 2; Short=Synaptic vesicle protein 2A;AltName: Full=Calcium regulator SV2A;

Provider

SWISS-PROT

Sequence

Polypeptide 742 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sv2a	synaptic vesicle glycoprotein 2a	21	115	3	15

Sequence references in MGI

J:59073 Crowder KM, et al., Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15268-73
J:59180 Janz R, et al., SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release. Neuron. 1999 Dec;24(4):1003-16
J:70828 Xu T, et al., SV2 modulates the size of the readily releasable pool of secretory vesicles. Nat Cell Biol. 2001 Aug;3(8):691-8
J:83149 Wang MM, et al., Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina. J Comp Neurol. 2003 May 19;460(1):106-22
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104817 Custer KL, et al., Synaptic vesicle protein 2 enhances release probability at quiescent synapses. J Neurosci. 2006 Jan 25;26(4):1303-13
J:108334 Dong M, et al., SV2 is the protein receptor for botulinum neurotoxin A. Science. 2006 Apr 28;312(5773):592-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89