Sequence Detail

ID/Version

Q9JIQ8 Q7TN04 Q9QY82 Q9JKC4 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transmembrane protease serine 2 {ECO:0000305}; EC=3.4.21.122 {ECO:0000250|UniProtKB:O15393};AltName: Full=Epitheliasin;AltName: Full=Plasmic transmembrane protein X;Contains: RecName: Full=Transmembrane protease serine 2 non-catalyt

Provider

SWISS-PROT

Sequence

Polypeptide 490 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tmprss2	transmembrane protease, serine 2	32	124	3	24

Sequence references in MGI

J:60563 Jacquinet E, et al., Cloning, genomic organization, chromosomal assignment and expression of a novel mosaic serine proteinase: epitheliasin. FEBS Lett. 2000 Feb 18;468(1):93-100
J:66811 Vaarala MH, et al., Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues. J Pathol. 2001 Jan;193(1):134-40
J:105558 Kim TS, et al., Phenotypic analysis of mice lacking the Tmprss2-encoded protease. Mol Cell Biol. 2006 Feb;26(3):965-75
J:214427 Sakai K, et al., The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses. J Virol. 2014 May;88(10):5608-16
J:214433 Tarnow C, et al., TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice. J Virol. 2014 May;88(9):4744-51
J:244166 Hatesuer B, et al., Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice. PLoS Pathog. 2013;9(12):e1003774
J:286343 Lam DK, et al., TMPRSS2, a novel membrane-anchored mediator in cancer pain. Pain. 2015 May;156(5):923-30