Sequence Detail

ID/Version

Q9JI99 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Sphingosine-1-phosphate phosphatase 1 {ECO:0000305}; Short=SPP; Short=SPPase1; Short=mSPP1; EC=3.1.3.- {ECO:0000269|PubMed:12411432};AltName: Full=Sphingosine-1-phosphatase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 430 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sgpp1	sphingosine-1-phosphate phosphatase 1	17	99	4	4

Sequence references in MGI

J:68325 Mandala SM, et al., Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7859-64
J:75337 Le Stunff H, et al., Characterization of murine sphingosine-1-phosphate phosphohydrolase. J Biol Chem. 2002 Mar 15;277(11):8920-7
J:79001 Le Stunff H, et al., Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis. J Cell Biol. 2002 Sep 16;158(6):1039-49
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:199597 Allende ML, et al., Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis. J Biol Chem. 2013 Jun 21;288(25):18381-91
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89