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Sequence Detail
Q9JI11 (UniProt | EBI) Last sequence update: 2000-10-01
Last annotation update: 2020-04-22
from provider
RecName: Full=Serine/threonine-protein kinase 4; EC=;AltName: Full=Mammalian STE20-like protein kinase 1; Short=MST-1;AltName: Full=STE20-like kinase MST1;Contains: RecName: Full=Serine/threonine-protein kinase 4 37kDa subunit;
Polypeptide 487 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Stk4 serine/threonine kinase 4 65 71 8 59
Sequence references in MGI J:69763 Lee KK, et al., MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J Biol Chem. 2001 Jun 1;276(22):19276-85
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:156531 Lu L, et al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1437-42
J:238700 Kwan J, et al., DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. Genes Dev. 2016 Dec 15;30(24):2696-2709

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory