Sequence Detail

ID/Version

Q9JHW2 Q9CTG9 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Omega-amidase NIT2 {ECO:0000303|PubMed:19596042}; EC=3.5.1.3 {ECO:0000269|PubMed:19596042, ECO:0000269|PubMed:28373563};AltName: Full=Nitrilase homolog 2 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 276 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nit2	nitrilase family, member 2	16	97	3	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143897 Barglow KT, et al., Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes. Biochemistry. 2008 Dec 23;47(51):13514-23
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:242138 Peracchi A, et al., Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3233-E3242
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89