Sequence Detail

ID/Version

Q9JHI8 Q8VCA3 Q8C3M1 Q3TF39 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=NADPH oxidase 4; EC=1.6.3.1 {ECO:0000250|UniProtKB:Q9NPH5};AltName: Full=Kidney oxidase-1; Short=KOX-1;AltName: Full=Kidney superoxide-producing NADPH oxidase;AltName: Full=Renal NAD(P)H-oxidase;AltName: Full=Superoxide-gener

Provider

SWISS-PROT

Sequence

Polypeptide 578 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nox4	NADPH oxidase 4	43	102	2	25

Sequence references in MGI

J:67599 Yang S, et al., A new superoxide-generating oxidase in murine osteoclasts. J Biol Chem. 2001 Feb 23;276(8):5452-8
J:90918 Suliman HB, et al., Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. Blood. 2004 Jul 1;104(1):43-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116373 Geiszt M, et al., Identification of renox, an NAD(P)H oxidase in kidney. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8010-4
J:341408 Ding Y, et al., Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone. J Pharm Pharmacol. 2005 Jan;57(1):111-6