Sequence Detail

ID/Version

Q9JHD1 Q640M9 Q3U142 (UniProt | EBI)

Last sequence update: 2008-03-18
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Histone acetyltransferase KAT2B; EC=2.3.1.48 {ECO:0000250|UniProtKB:Q92831};AltName: Full=Histone acetyltransferase PCAF {ECO:0000303|PubMed:11017084}; Short=Histone acetylase PCAF {ECO:0000303|PubMed:11017084};AltName: Full=

Provider

SWISS-PROT

Sequence

Polypeptide 813 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kat2b	K(lysine) acetyltransferase 2B	150	110	3	150

Sequence references in MGI

J:57302 Xu W, et al., Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Mol Cell Biol. 1998 Oct;18(10):5659-69
J:65002 Xu W, et al., Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175152 Gupta P, et al., Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11424-9
J:222684 Wansa KD, et al., The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine. J Biol Chem. 2003 Jul 4;278(27):24776-90
J:245382 Park SW, et al., SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells. Nat Struct Mol Biol. 2007 Jan;14(1):68-75