About   Help   FAQ
Due to maintenance, access to MGI may be intermittent starting at 7:30 AM ET Thursday, March 11.
Sequence Detail
Q9ESK9 Q8BRY9 Q9JK14 Q61384 E9QLQ2 Q3TXX2 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2021-02-10
from provider
RecName: Full=RB1-inducible coiled-coil protein 1;AltName: Full=Coiled-coil-forming protein 1;AltName: Full=FAK family kinase-interacting protein of 200 kDa; Short=FIP200;AltName: Full=LaXp180;
Polypeptide 1588 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Rb1cc1 RB1-inducible coiled-coil 1 44 74 8 14
Sequence references in MGI J:51752 Maucuer A, et al., Stathmin interaction with a putative kinase and coiled-coil-forming protein domains. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3100-4
J:66320 Pfeuffer T, et al., LaXp180, a mammalian ActA-binding protein, identified with the yeast two-hybrid system, co-localizes with intracellular Listeria monocytogenes. Cell Microbiol. 2000 Apr;2(2):101-14
J:77935 Chano T, et al., Isolation, characterization and mapping of the mouse and human RB1CC1 genes. Gene. 2002 May 29;291(1-2):29-34
J:97746 Bamba N, et al., Expression and regulation of RB1CC1 in developing murine and human tissues. Int J Mol Med. 2004 Oct;14(4):583-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103000 Watanabe R, et al., Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch. 2005 Sep;447(3):643-8
J:149848 Ganley IG, et al., ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem. 2009 May 1;284(18):12297-305
J:159947 Liang CC, et al., Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. J Biol Chem. 2010 Jan 29;285(5):3499-509
J:182941 Kageyama S, et al., The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella. Mol Biol Cell. 2011 Jul 1;22(13):2290-300
J:200458 Nishimura T, et al., FIP200 regulates targeting of Atg16L1 to the isolation membrane. EMBO Rep. 2013 Mar 1;14(3):284-91
J:245290 Gammoh N, et al., Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy. Nat Struct Mol Biol. 2013 Feb;20(2):144-9
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:281251 Bakula D, et al., WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017 May 31;8:15637
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.16
The Jackson Laboratory