Sequence Detail

ID/Version

Q9ES90 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=G-protein coupled receptor 35;AltName: Full=Kynurenic acid receptor; Short=KYNA receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 307 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpr35	G protein-coupled receptor 35	39	99	5	20

Sequence references in MGI

J:65000 Horikawa Y, et al., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct;26(2):163-75
J:116461 Wang J, et al., Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006 Aug 4;281(31):22021-8
J:260833 Agudelo LZ, et al., Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Cell Metab. 2018 Feb 6;27(2):378-392.e5
J:300275 Kaya B, et al., Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1(+) Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020 Aug 4;32(5):107979