Sequence Detail

ID/Version

Q9ES83 Q8C8L3 A2RS91 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Popeye domain-containing protein 1; Short=Popeye protein 1;AltName: Full=Blood vessel epicardial substance {ECO:0000312|MGI:MGI:1346013}; Short=mBVES;

Provider

SWISS-PROT

Sequence

Polypeptide 358 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Popdc1	popeye domain cAMP effector 1	70	106	3	9

Sequence references in MGI

J:57110 Reese DE, et al., bves: A novel gene expressed during coronary blood vessel development. Dev Biol. 1999 May 1;209(1):159-71
J:63597 Andree B, et al., Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. Dev Biol. 2000 Jul 15;223(2):371-82
J:74656 Andree B, et al., Mouse Pop1 is required for muscle regeneration in adult skeletal muscle. Mol Cell Biol. 2002 Mar;22(5):1504-12
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:102192 Osler ME, et al., Bves modulates epithelial integrity through an interaction at the tight junction. J Cell Sci. 2005 Oct 15;118(Pt 20):4667-78
J:157635 Hager HA, et al., Identification of a novel Bves function: regulation of vesicular transport. EMBO J. 2010 Feb 3;29(3):532-45
J:161106 Smith TK, et al., Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8298-303
J:184566 Froese A, et al., Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. J Clin Invest. 2012 Mar 1;122(3):1119-30
J:206498 Alcalay Y, et al., Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance. PLoS One. 2013;8(9):e71100
J:229320 Schindler RF, et al., POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking. J Clin Invest. 2016 Jan;126(1):239-53
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89