Sequence Detail

ID/Version

Q9ES34 Q8K068 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ubiquitin-protein ligase E3B; EC=2.3.2.26;AltName: Full=HECT-type ubiquitin transferase E3B;

Provider

SWISS-PROT

Sequence

Polypeptide 1070 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ube3b	ubiquitin protein ligase E3B	21	100	3	13

Sequence references in MGI

J:203652 Basel-Vanagaite L, et al., Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. 2012 Dec 7;91(6):998-1010
J:273879 Cheon S, et al., The ubiquitin ligase UBE3B, disrupted in intellectual disability and absent speech, regulates metabolic pathways by targeting BCKDK. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3662-3667
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333720 Ambrozkiewicz MC, et al., The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Mol Psychiatry. 2021 Jun;26(6):1980-1995