Sequence Detail

ID/Version

Q9ES17 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Interleukin-21; Short=IL-21;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 146 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il21	interleukin 21	31	98	3	20

Sequence references in MGI

J:65629 Parrish-Novak J, et al., Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000 Nov 2;408(6808):57-63
J:76043 Kasaian MT, et al., IL-21 Limits NK Cell Responses and Promotes Antigen-Specific T Cell Activation. A Mediator of the Transition from Innate to Adaptive Immunity. Immunity. 2002 Apr;16(4):559-69
J:190912 Karnowski A, et al., B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med. 2012 Oct 22;209(11):2049-64