Sequence Detail

ID/Version

Q9ERC8 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cell adhesion molecule DSCAM {ECO:0000305};AltName: Full=Down syndrome cell adhesion molecule homolog;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2013 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dscam	DS cell adhesion molecule	63	113	4	19

Sequence references in MGI

J:67853 Agarwala KL, et al., Dscam, a highly conserved gene in mammals, expressed in differentiating mouse brain. Biochem Biophys Res Commun. 2001 Mar 2;281(3):697-705
J:75517 Barlow GM, et al., Down syndrome cell adhesion molecule is conserved in mouse and highly expressed in the adult mouse brain. Cytogenet Cell Genet. 2001;94(3-4):155-62
J:129238 Fuerst PG, et al., Neurite arborization and mosaic spacing in the mouse retina require DSCAM. Nature. 2008 Jan 24;451(7177):470-4
J:143806 Ly A, et al., DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell. 2008 Jun 27;133(7):1241-54
J:155397 Fuerst PG, et al., DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina. Neuron. 2009 Nov 25;64(4):484-97
J:159129 Liu G, et al., DSCAM functions as a netrin receptor in commissural axon pathfinding. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2951-6
J:269564 Purohit AA, et al., Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse. J Biol Chem. 2012 Aug 3;287(32):27126-38