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Sequence Detail
ID/Version
Q9EQW6 Q9JKN4 (UniProt | EBI) Last sequence update: 2001-03-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Oligodendrocyte transcription factor 2; Short=Oligo2;
Provider SWISS-PROT
Sequence
Polypeptide 323 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Olig2 oligodendrocyte transcription factor 2 52 232 3 33
Sequence references in MGI J:60687 Zhou Q, et al., Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron. 2000 Feb;25(2):331-43
J:60773 Lu QR, et al., Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 2000 Feb;25(2):317-29
J:70984 Takebayashi H, et al., Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3. Mech Dev. 2000 Dec;99(1-2):143-8
J:75868 Lu QR, et al., Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
J:77821 Takebayashi H, et al., The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages. Curr Biol. 2002 Jul 9;12(13):1157-63
J:86307 Sun T, et al., Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex. J Neurosci. 2003 Oct 22;23(29):9547-56
J:87224 Liu R, et al., Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Development. 2003 Dec;130(25):6221-31
J:112231 Wang SZ, et al., An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development. 2006 Sep;133(17):3389-98
J:206509 Takebayashi H, et al., Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube. Mech Dev. 2002 May;113(2):169-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory