Sequence Detail

ID/Version

Q9EQQ0 Q8BNK2 Q9JLP7 Q9CUK3 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Histone-lysine N-methyltransferase SUV39H2; EC=2.1.1.355;AltName: Full=Histone H3-K9 methyltransferase 2; Short=H3-K9-HMTase 2;AltName: Full=Suppressor of variegation 3-9 homolog 2; Short=Su(var)3-9 homolog 2;

Provider

SWISS-PROT

Sequence

Polypeptide 477 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Suv39h2	suppressor of variegation 3-9 2	54	105	2	11

Sequence references in MGI

J:65972 O'Carroll D, et al., Isolation and characterization of suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. Mol Cell Biol. 2000 Dec;20(24):9423-33
J:72503 Peters AH, et al., Loss of the suv39h histone methyltransferases impairs Mammalian heterochromatin and genome stability. Cell. 2001 Nov 2;107(3):323-37
J:88268 Garcia-Cao M, et al., Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet. 2004 Jan;36(1):94-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:210023 Duong HA, et al., Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes. Nat Struct Mol Biol. 2014 Feb;21(2):126-32
J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89