Sequence Detail

ID/Version

Q9EPW2 Q3UQB0 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Krueppel-like factor 15;AltName: Full=Cardiovascular Krueppel-like factor;

Provider

SWISS-PROT

Sequence

Polypeptide 415 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Klf15	Kruppel-like transcription factor 15	45	107	3	15

Sequence references in MGI

J:92922 Gray S, et al., The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. J Biol Chem. 2002 Sep 13;277(37):34322-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121109 Fisch S, et al., Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7074-9
J:139283 Wang B, et al., The Kruppel-like factor KLF15 inhibits connective tissue growth factor (CTGF) expression in cardiac fibroblasts. J Mol Cell Cardiol. 2008 Aug;45(2):193-7
J:167880 Haldar SM, et al., Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation. Sci Transl Med. 2010 Apr 7;2(26):26ra26
J:181622 Jeyaraj D, et al., Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature. 2012 Mar 1;483(7387):96-9
J:186211 Mallipattu SK, et al., Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation. J Biol Chem. 2012 Jun 1;287(23):19122-35
J:203920 Lu Y, et al., Kruppel-like factor 15 is critical for vascular inflammation. J Clin Invest. 2013 Oct 1;123(10):4232-41