Sequence Detail

ID/Version

Q9EPW0 Q8CBJ8 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Inositol polyphosphate-4-phosphatase type I A;AltName: Full=Inositol polyphosphate 4-phosphatase type I;AltName: Full=Inositol polyphosphate 4-phosphatase-1 {ECO:0000303|PubMed:19325558}; Short=4-Ptase-1 {ECO:0000303|PubMed:19325558}

Provider

SWISS-PROT

Sequence

Polypeptide 939 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Inpp4a	inositol polyphosphate-4-phosphatase, type I	40	102	4	15

Sequence references in MGI

J:66416 Vyas P, et al., Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13696-701
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:157366 Ivetac I, et al., Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. EMBO Rep. 2009 May;10(5):487-93
J:161963 Sasaki J, et al., The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature. 2010 May 27;465(7297):497-501
J:230616 Nakatsu F, et al., Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway. J Cell Biol. 2015 Apr 13;209(1):85-95
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89