Sequence Detail

ID/Version

Q9EPU0 Q99PR4 Q6GYP5 Q3UG00 Q8K0N4 Q6PHQ5 (UniProt | EBI)

Last sequence update: 2007-05-29
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Regulator of nonsense transcripts 1 {ECO:0000312|MGI:MGI:107995}; EC=3.6.4.12 {ECO:0000250|UniProtKB:Q92900}; EC=3.6.4.13 {ECO:0000250|UniProtKB:Q92900};AltName: Full=ATP-dependent helicase RENT1 {ECO:0000303|PubMed:11152657}

Provider

SWISS-PROT

Sequence

Polypeptide 1124 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Upf1	UPF1 RNA helicase and ATPase	61	100	3	12

Sequence references in MGI

J:35791 Perlick HA, et al., Mammalian orthologues of a yeast regulator of nonsense transcript stability. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10928-32
J:67076 Medghalchi SM, et al., Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum Mol Genet. 2001 Jan 15;10(2):99-105
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:232557 Fanourgakis G, et al., Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay. PLoS Genet. 2016 May;12(5):e1005857
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:335610 Qian B, et al., RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis. Sci Adv. 2022 Aug 26;8(34):eabq2945