Sequence Detail

ID/Version

Q9EPL2 Q7TS67 Q8K103 A2A800 B2KFP1 Q69ZV9 B2KFP2 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Calsyntenin-1 {ECO:0000305};AltName: Full=Alcadein-alpha {ECO:0000303|PubMed:17332754}; Short=Alc-alpha {ECO:0000303|PubMed:17332754};Contains: RecName: Full=Soluble Alc-alpha {ECO:0000250|UniProtKB:O94985}; Short=SAlc-alp

Provider

SWISS-PROT

Sequence

Polypeptide 979 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clstn1	calsyntenin 1	61	104	3	23

Sequence references in MGI

J:67326 Vogt L, et al., Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. Mol Cell Neurosci. 2001 Jan;17(1):151-66
J:80943 Hintsch G, et al., The calsyntenins-a family of postsynaptic membrane proteins with distinct neuronal expression patterns. Mol Cell Neurosci. 2002 Nov;21(3):393-409
J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:113428 Konecna A, et al., Calsyntenin-1 docks vesicular cargo to kinesin-1. Mol Biol Cell. 2006 Aug;17(8):3651-63
J:119815 Araki Y, et al., The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J. 2007 Mar 21;26(6):1475-86
J:211830 Um JW, et al., Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep. 2014 Mar 27;6(6):1096-109
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:329050 Mori K, et al., Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior. Mol Brain. 2022 Mar 12;15(1):23