Sequence Detail

ID/Version

Q9EP73 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Programmed cell death 1 ligand 1; Short=PD-L1; Short=PDCD1 ligand 1; Short=Programmed death ligand 1;AltName: Full=B7 homolog 1; Short=B7-H1;AltName: CD_antigen=CD274;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 290 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd274	CD274 antigen	75	100	3	39

Sequence references in MGI

J:64991 Freeman GJ, et al., Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000 Oct 2;192(7):1027-34
J:67842 Latchman Y, et al., PD-L2 is a second ligand for PD-I and inhibits T cell activation. Nat Immunol. 2001 Mar;2(3):261-8
J:68077 Tamura H, et al., B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood. 2001 Mar 15;97(6):1809-16