Sequence Detail

ID/Version

Q9D9D3 B7ZNH3 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=TBC1 domain family member 21 {ECO:0000312|MGI:MGI:1921536};AltName: Full=Male germ cell Rab GTPase-activating protein {ECO:0000303|PubMed:21128978};

Provider

SWISS-PROT

Sequence

Polypeptide 336 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tbc1d21	TBC1 domain family, member 21	26	96	2	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:177986 Lin YH, et al., Identification and characterization of a novel Rab GTPase-activating protein in spermatids. Int J Androl. 2011 Oct;34(5 Pt 2):e358-67
J:299845 Wang YY, et al., Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice. PLoS Genet. 2020 Sep;16(9):e1009020
J:302631 Shimada K, et al., ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2018355118
J:314551 Ke CC, et al., TBC1D21 Potentially Interacts with and Regulates Rap1 during Murine Spermatogenesis. Int J Mol Sci. 2018 Oct 23;19(11):3292