Sequence Detail

ID/Version

Q9D8I1 Q6P3D3 Q8K2M5 Q8BU13 D2IYS1 (UniProt | EBI)

Last sequence update: 2008-02-26
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Marginal zone B- and B1-cell-specific protein;AltName: Full=Plasma cell-induced resident endoplasmic reticulum protein; Short=Plasma cell-induced resident ER protein; Short=pERp1;AltName: Full=Proapoptotic caspase adapter pro

Provider

SWISS-PROT

Sequence

Polypeptide 188 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mzb1	marginal zone B and B1 cell-specific protein 1	22	97	2	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:153676 van Anken E, et al., Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17019-24
J:156740 Shimizu Y, et al., pERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulin. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17013-8
J:167004 Flach H, et al., Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity. 2010 Nov 24;33(5):723-35
J:174846 Zhang H, et al., Novel hormone-regulated genes in visceral adipose tissue: cloning and identification of proinflammatory cytokine-like mouse and human MEDA-7: implications for obesity, insulin resistance and the metabolic syndrome. Diabetologia. 2011 Sep;54(9):2368-80
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89