Sequence Detail

ID/Version

Q9D8F1 Q8R1Y9 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 {ECO:0000305};AltName: Full=Alkylated DNA repair protein alkB homolog 4 {ECO:0000303|PubMed:23673617};AltName: Full=DNA N6-methyl adenine demethylase ALKBH4 {ECO:0000305}; EC=1

Provider

SWISS-PROT

Sequence

Polypeptide 300 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Alkbh4	alkB homolog 4, lysine demethylase	36	96	3	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:205739 Li MM, et al., ALKBH4-dependent demethylation of actin regulates actomyosin dynamics. Nat Commun. 2013;4:1832
J:221080 Nilsen A, et al., ALKBH4 depletion in mice leads to spermatogenic defects. PLoS One. 2014;9(8):e105113
J:278437 Kweon SM, et al., An Adversarial DNA N(6)-Methyladenine-Sensor Network Preserves Polycomb Silencing. Mol Cell. 2019 Jun 20;74(6):1138-1147.e6