Sequence Detail

ID/Version

Q9D8B7 Q8BT59 Q9EPK4 Q9D1M9 (UniProt | EBI)

Last sequence update: 2005-05-10
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Junctional adhesion molecule C; Short=JAM-C;AltName: Full=JAM-2 {ECO:0000303|PubMed:11053409, ECO:0000303|PubMed:11739175};AltName: Full=Junctional adhesion molecule 3; Short=JAM-3;Contains: RecName: Full=Soluble form of JAM

Provider

SWISS-PROT

Sequence

Polypeptide 310 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Jam3	junction adhesion molecule 3	119	104	4	9

Sequence references in MGI

J:68971 Aurrand-Lions MA, et al., Cloning of JAM-2 and JAM-3: an emerging junctional adhesion molecular family?. Curr Top Microbiol Immunol. 2000;251:91-8
J:92665 Gliki G, et al., Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C. Nature. 2004 Sep 16;431(7006):320-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106527 Lamagna C, et al., Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion. Mol Biol Cell. 2005 Oct;16(10):4992-5003
J:172999 Lamagna C, et al., Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Cancer Res. 2005 Jul 1;65(13):5703-10
J:225263 Arcangeli ML, et al., Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells. Stem Cells. 2014 Apr;32(4):1043-54
J:241919 Cartier-Michaud A, et al., Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis. PLoS Genet. 2017 Jun;13(6):e1006803
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89