Sequence Detail

ID/Version

Q9D842 Q8BZL5 Q99LX6 (UniProt | EBI)

Last sequence update: 2005-08-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Aprataxin and PNK-like factor; EC=3.1.-.- {ECO:0000250|UniProtKB:Q8IW19};AltName: Full=Apurinic-apyrimidinic endonuclease APLF;

Provider

SWISS-PROT

Sequence

Polypeptide 499 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aplf	aprataxin and PNKP like factor	80	98	3	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:168260 Rulten SL, et al., PARP-3 and APLF function together to accelerate nonhomologous end-joining. Mol Cell. 2011 Jan 7;41(1):33-45
J:247123 Syed KM, et al., Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts. J Cell Sci. 2016 Dec 15;129(24):4576-4591
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311886 Varghese PC, et al., Histone chaperone APLF level dictates the implantation of mouse embryos. J Cell Sci. 2021 Jan 13;134(1):jcs246900