Sequence Detail

ID/Version

Q9D6R2 Q8C8A1 Q3UAM8 Q9D1L1 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial {ECO:0000250|UniProtKB:P50213}; EC=1.1.1.41 {ECO:0000250|UniProtKB:P50213};AltName: Full=Isocitric dehydrogenase subunit alpha;AltName: Full=NAD(+)-specific ICDH subunit alp

Provider

SWISS-PROT

Sequence

Polypeptide 366 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Idh3a	isocitrate dehydrogenase 3 (NAD+) alpha	37	104	3	16

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:267900 Findlay AS, et al., Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function. Dis Model Mech. 2018 Dec 18;11(12):dmm036426
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89