Sequence Detail

ID/Version

Q9D1N4 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Protein myomaker {ECO:0000303|PubMed:23868259};AltName: Full=Myoblast fusion maker {ECO:0000303|PubMed:23868259};AltName: Full=Transmembrane protein 8C;

Provider

SWISS-PROT

Sequence

Polypeptide 221 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mymk	myomaker, myoblast fusion factor	11	105	2	4

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:200444 Millay DP, et al., Myomaker is a membrane activator of myoblast fusion and muscle formation. Nature. 2013 Jul 18;499(7458):301-5
J:216211 Millay DP, et al., Myomaker is essential for muscle regeneration. Genes Dev. 2014 Aug 1;28(15):1641-6
J:242061 Bi P, et al., Control of muscle formation by the fusogenic micropeptide myomixer. Science. 2017 Apr 21;356(6335):323-327
J:243485 Di Gioia SA, et al., A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nat Commun. 2017 Jul 06;8:16077
J:246344 Gamage DG, et al., Insights into the localization and function of myomaker during myoblast fusion. J Biol Chem. 2017 Oct 20;292(42):17272-17289
J:249295 He J, et al., miR-491 inhibits skeletal muscle differentiation through targeting myomaker. Arch Biochem Biophys. 2017 Jul 1;625-626:30-38
J:256675 Goh Q, et al., Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy. Elife. 2017 Feb 10;6:e20007
J:269537 Leikina E, et al., Myomaker and Myomerger Work Independently to Control Distinct Steps of Membrane Remodeling during Myoblast Fusion. Dev Cell. 2018 Sep 24;46(6):767-780.e7