Sequence Detail

ID/Version

Q9D154 Q5SUV7 Q3TV23 Q9D0S8 Q9D7S8 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Leukocyte elastase inhibitor A;AltName: Full=Serine protease inhibitor EIA;AltName: Full=Serpin B1a;

Provider

SWISS-PROT

Sequence

Polypeptide 379 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Serpinb1a	serine (or cysteine) peptidase inhibitor, clade B, member 1a	34	100	4	8

Sequence references in MGI

J:75161 Kaiserman D, et al., Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics. 2002 Mar;79(3):349-62
J:79876 Benarafa C, et al., Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1). J Biol Chem. 2002 Nov 1;277(44):42028-33
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:125918 Benarafa C, et al., The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection. J Exp Med. 2007 Aug 6;204(8):1901-9
J:174751 Benarafa C, et al., SerpinB1 protects the mature neutrophil reserve in the bone marrow. J Leukoc Biol. 2011 Jul;90(1):21-9
J:232736 El Ouaamari A, et al., SerpinB1 Promotes Pancreatic beta Cell Proliferation. Cell Metab. 2016 Jan 12;23(1):194-205
J:273511 Choi YJ, et al., SERPINB1-mediated checkpoint of inflammatory caspase activation. Nat Immunol. 2019 Mar;20(3):276-287
J:273525 Benarafa C, The SerpinB1 knockout mouse a model for studying neutrophil protease regulation in homeostasis and inflammation. Methods Enzymol. 2011;499:135-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89