Sequence Detail

ID/Version

Q9CZD3 Q3TMM4 Q3UK01 Q8VC67 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Glycine--tRNA ligase; EC=6.1.1.14 {ECO:0000250|UniProtKB:P41250};AltName: Full=Diadenosine tetraphosphate synthetase; Short=Ap4A synthetase; EC=2.7.7.- {ECO:0000250|UniProtKB:P41250};AltName: Full=Glycyl-tRNA syntheta

Provider

SWISS-PROT

Sequence

Polypeptide 729 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gars1	glycyl-tRNA synthetase 1	61	99	3	24

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112221 Seburn KL, et al., An Active Dominant Mutation of Glycyl-tRNA Synthetase Causes Neuropathy in a Charcot-Marie-Tooth 2D Mouse Model. Neuron. 2006 Sep 21;51(6):715-26
J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:226761 He W, et al., CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015 Oct 29;526(7575):710-4
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89