Sequence Detail

ID/Version

Q9CZ57 Q9D7F0 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=5-cytosine rRNA methyltransferase NSUN4; EC=2.1.1.- {ECO:0000250|UniProtKB:Q95XR2};AltName: Full=5-cytosine tRNA methyltransferase NSUN4 {ECO:0000305}; EC=2.1.1.- {ECO:0000250|UniProtKB:Q95XR2};AltName: Full=NOL1/NOP2/Sun dom

Provider

SWISS-PROT

Sequence

Polypeptide 381 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nsun4	NOL1/NOP2/Sun domain family, member 4	11	97	2	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175816 Camara Y, et al., MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cell Metab. 2011 May 4;13(5):527-39
J:211012 Metodiev MD, et al., NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly. PLoS Genet. 2014 Feb;10(2):e1004110