Sequence Detail

ID/Version

Q9CYN9 A2BDN5 Q91YU5 Q8BVU6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Renin receptor;AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2;AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2;AltName: Full=Renin/prorenin receptor;Contains: RecName: Full=Renin receptor extracel

Provider

SWISS-PROT

Sequence

Polypeptide 350 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	68	99	3	56

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:226483 Dubos A, et al., Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration. Hum Mol Genet. 2015 Dec 1;24(23):6736-55
J:251881 Rujano MA, et al., Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects. J Exp Med. 2017 Dec 4;214(12):3707-3729
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296116 Hirose T, et al., ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration. J Clin Invest. 2019 Apr 15;129(5):2145-2162