Sequence Detail

ID/Version

Q9CXB8 Q69ZH5 Q8BLT9 (UniProt | EBI)

Last sequence update: 2006-11-28
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Alpha-protein kinase 1 {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q96QP1};

Provider

SWISS-PROT

Sequence

Polypeptide 1231 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Alpk1	alpha-kinase 1	29	96	3	10

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:264436 Zhou P, et al., Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose. Nature. 2018 Aug 15;
J:306639 Williams LB, et al., ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder. Genet Med. 2019 Sep;21(9):2103-2115
J:329824 Chen M, et al., Motor coordination deficits in Alpk1 mutant mice with the inserted piggyBac transposon. BMC Neurosci. 2011 Jan 5;12:1