Sequence Detail

ID/Version

Q9CWS1 Q9DCH3 Q3UBK5 Q8R161 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase RNF135 {ECO:0000305}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q8IUD6};AltName: Full=RING finger protein 135;AltName: Full=RING-type E3 ubiquitin transferase RNF135 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 417 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rnf135	ring finger protein 135	53	100	2	52

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:260659 Oshiumi H, et al., The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection. Cell Host Microbe. 2010 Dec 16;8(6):496-509
J:261333 Oshiumi H, et al., A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses. PLoS Pathog. 2013;9(8):e1003533
J:281202 Shi Y, et al., Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity. Nat Commun. 2017 May 4;8:15138