Sequence Detail

ID/Version

Q9CWS0 Q3UF65 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 {ECO:0000305}; Short=DDAH-1; Short=Dimethylarginine dimethylaminohydrolase 1; EC=3.5.3.18 {ECO:0000269|PubMed:17273169, ECO:0000269|PubMed:21493890, ECO:0000269|PubM

Provider

SWISS-PROT

Sequence

Polypeptide 285 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ddah1	dimethylarginine dimethylaminohydrolase 1	31	105	3	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121719 Leiper J, et al., Disruption of methylarginine metabolism impairs vascular homeostasis. Nat Med. 2007 Feb;13(2):198-203
J:182373 Hu X, et al., Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1540-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:337786 Ragavan VN, et al., A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase. Nat Commun. 2023 Jun 9;14(1):3392