Sequence Detail

ID/Version

Q9CWR0 Q8R1Q4 Q3TYF3 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2023-11-08

Sequence description from provider

RecName: Full=Rho guanine nucleotide exchange factor 25;AltName: Full=Guanine nucleotide exchange factor GEFT;AltName: Full=Rac/Cdc42/Rho exchange factor GEFT;AltName: Full=RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT;AltName: Full=p63RhoGEF;

Provider

SWISS-PROT

Sequence

Polypeptide 618 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arhgef25	Rho guanine nucleotide exchange factor 25	9	106	4	10

Sequence references in MGI

J:82956 Guo X, et al., A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration. J Biol Chem. 2003 Apr 11;278(15):13207-15
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103756 Bryan BA, et al., Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. Mol Cell Biol. 2005 Dec;25(24):11089-101
J:161106 Smith TK, et al., Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8298-303