Sequence Detail

ID/Version

Q9CQV6 Q3U9W5 Q9D1R0 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Microtubule-associated proteins 1A/1B light chain 3B {ECO:0000305};AltName: Full=Autophagy-related protein LC3 B;AltName: Full=Autophagy-related ubiquitin-like modifier LC3 B;AltName: Full=MAP1 light chain 3-like protein 2;AltName: Full=MAP1

Provider

SWISS-PROT

Sequence

Polypeptide 125 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Map1lc3b	microtubule-associated protein 1 light chain 3 beta	44	123	4	6

Sequence references in MGI

J:70539 Mizushima N, et al., Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol. 2001 Feb 19;152(4):657-68
J:87279 Hemelaar J, et al., A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L. J Biol Chem. 2003 Dec 19;278(51):51841-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:170318 Itoh T, et al., OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J Cell Biol. 2011 Mar 7;192(5):839-53
J:198986 Umebayashi H, et al., Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation. Biochem Biophys Res Commun. 2013 Mar 8;432(2):268-74
J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:266073 Toledo M, et al., Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1. Cell Metab. 2018 Aug 7;28(2):268-281.e4
J:273835 Defourny J, et al., Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8010-8017
J:313627 Reggio A, et al., Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. EMBO Rep. 2021 Sep 6;22(9):e52289
J:313858 Tamargo-Gomez I, et al., ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration. Cell Death Differ. 2021 Sep;28(9):2651-2672