Sequence Detail

ID/Version

Q99PV8 Q8C2I1 Q9JLF8 Q99PV7 Q99PV6 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=B-cell lymphoma/leukemia 11B; Short=BCL-11B;AltName: Full=B-cell CLL/lymphoma 11B;AltName: Full=COUP-TF-interacting protein 2;AltName: Full=Radiation-induced tumor suppressor gene 1 protein; Short=mRit1;

Provider

SWISS-PROT

Sequence

Polypeptide 884 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bcl11b	B cell leukemia/lymphoma 11B	67	227	4	25

Sequence references in MGI

J:61589 Avram D, et al., Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J Biol Chem. 2000 Apr 7;275(14):10315-22
J:82132 Wakabayashi Y, et al., Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas. Biochem Biophys Res Commun. 2003 Feb 7;301(2):598-603
J:83651 Wakabayashi Y, et al., Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol. 2003 Jun;4(6):533-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:139460 Cismasiu VB, et al., BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes. Blood. 2006 Oct 15;108(8):2695-702
J:193101 Tirard M, et al., In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21122-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87