About   Help   FAQ
Sequence Detail
ID/Version
Q99P58 Q8CIX0 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Ras-related protein Rab-27B; EC=3.6.5.2 {ECO:0000250|UniProtKB:O00194};
Provider SWISS-PROT
Sequence
Polypeptide 218 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Rab27b RAB27B, member RAS oncogene family 67 98 3 13
Sequence references in MGI J:67620 Ramalho JS, et al., Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene. BMC Genet. 2001;2(1):2
J:76325 Zhao S, et al., Involvement of Rab27b in the regulated secretion of pituitary hormones. Endocrinology. 2002 May;143(5):1817-24
J:80040 Fukuda M, et al., Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin. J Biol Chem. 2002 Nov 8;277(45):43096-103
J:83108 Fukuda M, Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. J Biol Chem. 2003 Apr 25;278(17):15373-80
J:116278 Saegusa C, et al., Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes Cells. 2006 Jun;11(6):623-31
J:155184 Kukimoto-Niino M, et al., Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure. 2008 Oct 8;16(10):1478-90
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory