Sequence Detail

ID/Version

Q99NF1 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Carotenoid-cleaving dioxygenase, mitochondrial {ECO:0000305|PubMed:21106934}; EC=1.13.11.- {ECO:0000269|PubMed:21106934}; EC=1.13.11.71 {ECO:0000269|PubMed:21106934};AltName: Full=B-diox-II {ECO:0000303|PubMed:11278918};AltNa

Provider

SWISS-PROT

Sequence

Polypeptide 532 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bco2	beta-carotene oxygenase 2	37	98	5	9

Sequence references in MGI

J:74948 Kiefer C, et al., Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A. J Biol Chem. 2001 Apr 27;276(17):14110-6
J:170742 Amengual J, et al., A mitochondrial enzyme degrades carotenoids and protects against oxidative stress. FASEB J. 2011 Mar;25(3):948-59