Sequence Detail

ID/Version

Q99NA2 Q8C1I7 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcription factor Atoh8 {ECO:0000305};AltName: Full=Helix-loop-helix protein mATH-6 {ECO:0000305|PubMed:11733035}; Short=mATH6 {ECO:0000303|PubMed:11733035};AltName: Full=Okadin {ECO:0000303|Ref.1};AltName: Full=Protein atonal hom

Provider

SWISS-PROT

Sequence

Polypeptide 322 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atoh8	atonal bHLH transcription factor 8	57	115	3	10

Sequence references in MGI

J:87008 Inoue C, et al., Math6, a bHLH gene expressed in the developing nervous system, regulates neuronal versus glial differentiation. Genes Cells. 2001 Nov;6(11):977-86
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113418 Ross MD, et al., Math6 expression during kidney development and altered expression in a mouse model of glomerulosclerosis. Dev Dyn. 2006 Nov;235(11):3102-9
J:137207 Lynn FC, et al., Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430
J:203454 Rawnsley DR, et al., The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40
J:210057 Ejarque M, et al., Characterization of the transcriptional activity of the basic helix-loop-helix (bHLH) transcription factor Atoh8. Biochim Biophys Acta. 2013 Nov;1829(11):1175-83
J:220502 Balakrishnan-Renuka A, et al., ATOH8, a regulator of skeletal myogenesis in the hypaxial myotome of the trunk. Histochem Cell Biol. 2014 Mar;141(3):289-300