Sequence Detail

ID/Version

Q99MH6 Q3TLD6 Q8K200 Q91Y46 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Protein naked cuticle homolog 1; Short=Naked-1; Short=mNkd; Short=mNkd1;

Provider

SWISS-PROT

Sequence

Polypeptide 471 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nkd1	naked cuticle 1	23	121	3	6

Sequence references in MGI

J:69580 Wharton KA Jr, et al., Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling. Dev Biol. 2001 Jun 1;234(1):93-106
J:95048 Ishikawa A, et al., Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling. Mech Dev. 2004 Dec;121(12):1443-53
J:95901 Li Q, et al., A targeted mutation of Nkd1 impairs mouse spermatogenesis. J Biol Chem. 2005 Jan 28;280(4):2831-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106658 Boerboom D, et al., Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model. Cancer Res. 2006 Feb 15;66(4):1964-73
J:122353 Zhang S, et al., Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. Mol Cell Biol. 2007 Jun;27(12):4454-64
J:187577 Creyghton MP, et al., PR72, a novel regulator of Wnt signaling required for Naked cuticle function. Genes Dev. 2005 Feb 1;19(3):376-86
J:187580 Yan D, et al., Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3802-7