Sequence Detail

ID/Version

Q99KU1 Q8BZ16 Q3UF13 A3KGL4 Q8BZK8 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dehydrodolichyl diphosphate synthase complex subunit Dhdds {ECO:0000305}; EC=2.5.1.87 {ECO:0000250|UniProtKB:Q86SQ9};AltName: Full=Cis-isoprenyltransferase {ECO:0000250|UniProtKB:Q86SQ9}; Short=CIT {ECO:0000250|UniProtKB:Q86S

Provider

SWISS-PROT

Sequence

Polypeptide 333 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dhdds	dehydrodolichyl diphosphate synthase	27	97	3	16

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:287362 DeRamus ML, et al., Selective Ablation of Dehydrodolichyl Diphosphate Synthase in Murine Retinal Pigment Epithelium (RPE) Causes RPE Atrophy and Retinal Degeneration. Cells. 2020 Mar 21;9(3):771
J:303192 Ramachandra Rao S, et al., Lack of Overt Retinal Degeneration in a K42E Dhdds Knock-In Mouse Model of RP59. Cells. 2020 Apr 7;9(4):896
J:306729 Ramachandra Rao S, et al., Retinal Degeneration Caused by Rod-Specific Dhdds Ablation Occurs without Concomitant Inhibition of Protein N-Glycosylation. iScience. 2020 Jun 26;23(6):101198
J:338107 Nguyen MN, et al., A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission. Cell Death Dis. 2023 Jul 13;14(7):420