Sequence Detail

ID/Version

Q99K23 Q8C5I0 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ufm1-specific protease 2 {ECO:0000303|PubMed:17182609}; Short=UfSP2 {ECO:0000303|PubMed:17182609}; EC=3.4.22.- {ECO:0000269|PubMed:21228277};

Provider

SWISS-PROT

Sequence

Polypeptide 461 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ufsp2	UFM1-specific peptidase 2	35	100	3	6

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:120365 Kang SH, et al., Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem. 2007 Feb 23;282(8):5256-62
J:170641 Ha BH, et al., Structure of Ubiquitin-fold Modifier 1-specific Protease UfSP2. J Biol Chem. 2011 Mar 25;286(12):10248-57
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:300137 Balce DR, et al., UFMylation inhibits the proinflammatory capacity of interferon-gamma-activated macrophages. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2011763118