Sequence Detail

ID/Version

Q99JZ7 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=ERBB receptor feedback inhibitor 1;AltName: Full=Mitogen-inducible gene 6 protein homolog; Short=MIG-6;

Provider

SWISS-PROT

Sequence

Polypeptide 461 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Errfi1	ERBB receptor feedback inhibitor 1	116	98	3	18

Sequence references in MGI

J:109556 Ferby I, et al., Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation. Nat Med. 2006 May;12(5):568-73
J:150007 Jeong JW, et al., Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8677-82
J:153715 Jin N, et al., Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct;136(19):3347-56
J:154203 Descot A, et al., Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction. Mol Cell. 2009 Aug 14;35(3):291-304
J:159742 Kim TH, et al., ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod. 2010 Apr;82(4):706-13
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89