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Sequence Detail
Q99246 Q8R2J0 Q8R2I9 Q7TSD2 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2019-09-18
from provider
RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1D;AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 2;AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.3;
Polypeptide 2179 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 71 17 8 11
Sequence references in MGI J:26177 Perez-Reyes E, et al., Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes. J Biol Chem. 1990 Nov 25;265(33):20430-6
J:63515 Platzer J, et al., Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels. Cell. 2000 Jul 7;102(1):89-97
J:72316 Namkung Y, et al., Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation. J Clin Invest. 2001 Oct;108(7):1015-22
J:86180 Xu M, et al., Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice. J Biol Chem. 2003 Oct 17;278(42):40837-41
J:99822 Mangoni ME, et al., Functional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activity. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5543-8
J:263450 Brandt A, et al., Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. J Neurosci. 2005 Dec 14;25(50):11577-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory