Sequence Detail

ID/Version

Q925U4 Q8CFM1 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 652 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Edem1	ER degradation enhancer, mannosidase alpha-like 1	36	101	3	11

Sequence references in MGI

J:76183 Hosokawa N, et al., A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. EMBO Rep. 2001 May;2(5):415-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:169878 Ushioda R, et al., ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science. 2008 Jul 25;321(5888):569-72
J:170851 Hagiwara M, et al., Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5. Mol Cell. 2011 Feb 18;41(4):432-44